Yes. We are standardizing the protocol of Karyotyping Cattle, Buffalo and Dog. It will take a couple of months to initiate this facility at College of Animal Biotechnology.
The stakeholders will need to provide fresh 3-5 ml blood sample.
The cost for Kartotyping per sample can be approximately Rs. 1800.
The results of Karyotyping can be expected in 10 to 15 days.
The facility is being developed as it may take maximum on year to extend the facility for cattle and buffalo. For dog’s parentage determination, the process is underway.
Parentage determination is done through DNA finger printing, which uses a set of microsatellite markers (a kind of DNA polymorphism). In simple language, as the left- thumb print (i.e. fingerprint) is unique to all human being, no two persons are expected to have same fingerprint, similarly, the array of microsatellite markers will create unique signature for each of the individuals under study. We use the same technique to differentiate the biological parents from other putative parents.
Exposure to specific hormones, namely progesterone, increases the risk for developing mammary cancers in dogs. The incidence of these tumors is related to whether a dog is intact or has had an ovariohysterectomy (i.e. has been spayed). Dogs spayed prior to their first heat {also milled estrus) have only a 0.5% risk of developing mammary tumor(s). Other predisposing factors include breed, age. Sex, diet and lifestyle of the dogs.
Conventionally by histopathology and radiography. Certain tumor markers can be measured to diagnose CMT.
The prognosis for dogs with benign tumors is excellent. About half of the dogs with malignant tumors also have an excellent prognosis with surgery alone. Those with malignant tumors are at risk for the spread of their tumor. This leads to illness and poor quality of life, with survival times usually less than one year. Dogs with inflammatory mamma, carcinoma and mammary sarcomas leave a poor prognosis, on the order of weeks to months. Early detection of tumours is key for long-term survival.
Wide surgical resection is recommended for malignant mammary masses. Benign tumors require less aggressive surgical margins. Surgery is the only treatment required for benign tumors and some malignant tumors. Dogs with large tumors, high-grade tumors, tumors that have already spread certain histological types are at higher risk for re-growth mid spread following surgery. Multiple tumors can be removed at the same time. The role d chemotherapy for dogs with malignant mammary tumors is not well-established. NSAIDs play a role in treating many different types or carcinomas.
